In the realm of traditional medicine, Mesima mushroom holds a significant place in both our ancient Indian system of medicine and Traditional Chinese Medicine (TCM). Legends and folk remedies speak of its remarkable healing properties offering hope and respite from various ailments that have plagued humanity for centuries.
Known by the intriguing names of black hoof mushroom or Mesima mushroom, this basidiomycete fungus has captured the attention of healers and researchers alike. Its spores develop in club-shaped structures known as Basidia, a characteristic feature of basidiomycetes. Mesima mushroom has gained immense popularity in India, Japan and Korea, particularly in Korea where it has been extensively studied and revered as a miraculous medicine. One of the most remarkable qualities of Mesima mushroom lies in its potent anti-tumor activity among the hymenomycetes, a fungal grouping known for its medicinal properties. Their studies have demonstrated its broad immunostimulant activity, powerful anti-cancer properties and its ability to enhance the effectiveness of existing chemotherapeutic drugs. According to Traditional Ancient System of Bharatiya Medicine carried by our tribal community of the almighty Himalayas as well as Traditional Chinese Medicine, Mesima mushroom has been used in the treatment of very serious health issues and nowadays is studied for cancer, diabetes, HIV, angina, leucorrhoea, diarrhea and even accelerated wound healing properties by advance sciences.
Globally, researchers have delved into the depths of Mesima mushroom’s composition, especially in Korea and Japan. They have discovered that P. linteus, the scientific name for Mesima mushroom, contains polysaccharide and proteoglycan components along with flavonoids and antioxidants. These constituents contribute to its anti-inflammatory, cytotoxic and antiviral effects. The recent reports surrounding Mesima mushroom have been nothing short of extraordinary. It acts as a potent stimulus demonstrating remarkable positive effects in numerous cancer patients. Astounding case studies have emerged such as the revocation of rapidly progressive bone metastasis in a prostate cancer patient who consumed Mesima mushroom. Another case showcased the spontaneous regression of tumors in a 65-year-old man with a large hepatocellular cancer and metastasis in various skeletal regions. In this instance, the patient opted for P. linteus instead of conventional treatment and experienced remarkable healing.
Mesima mushroom has also shown promising results in lung and breast cancer cells, displaying synergistic effects when combined with chemotherapeutic drugs. Notably, in vitro studies have revealed its remarkable ability to inhibit the growth of bladder cancer cells particularly when combined with vitamin C. Moreover, Mesima mushroom has been hailed as a magical remedy for infertility in our tribal community as a folk remedy. In cases where infertility is associated with elevated cytokine and natural killer (NK) cell levels, supplementation with Mesima mushroom mycelial biomass has shown significant improvements in immune parameters.
While scientific research continues to explore the biochemistry of this wondrous fungus aiming to identify potential pharmaceutical substances, it is crucial to acknowledge the rich tapestry of folk remedies and stories that have woven Mesima mushroom into the fabric of traditional medicine. With its long history of use in ancient healing practices, Mesima mushroom stands as a beacon of hope in our quest to overcome health pandemics such as cancer.
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